The compound 8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C18H28N4
-Molecular weight: 300.44g/mol
-Melting point: 189-192 degrees Celsius
-Solubility: It has certain solubility in some organic solvents, such as ethanol and chloroform
Use:
-The compound has certain applications in the field of medicinal chemistry. It can be used to synthesize various bioactive compounds, such as drug molecules and chemical probes. It can also be used for the exploration and validation of synthetic strategies in drug development.
Preparation Method:
The preparation method involves a multi-step synthesis, and a possible synthetic route is briefly described below:
1.5-isopropyl -3-methyl -4H-1, 2,4-triazole -4-iodide was synthesized by two consecutive steps of Hantzsch triazole synthesis.
2. The benzyl compound is synthesized by using the old Xiufu reaction and the reactant in the previous step is subjected to a prior cyclization reaction under alkaline conditions.
3. After a series of protection reactions, the target compound is obtained by elimination reaction reduction.
Safety Information:
-Due to the nature and use of the compound, it is necessary to follow appropriate laboratory safety practices when handling and handling the compound.
-The toxicity and harmfulness of this compound are not fully understood. Appropriate personal protective measures should be taken, such as wearing gloves and goggles, and ensuring that the operation is carried out in well-ventilated conditions.
-If waste or solution of this compound is to be disposed of, it should be disposed of in accordance with local regulations.